MyBioSource.com's mAb anti-Human SAA is a Mouse monoclonal antibody. The mAb anti-Human SAA Antibody was generated using SAA1 as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: ELISA.
Description
SAA is an acute phase protein and a sensitive inflammatory marker. Cytokines such aslL-l, IL-6 and TNFalpha stimulates hepatocytes to produce and release SAA. In acute phase, SAA in blood can increase to more than 1,000 folds of normal level. Prolonged and repeated elevation of SAA results in abnormal deposition of amyloid proteins in organ or tissue in insoluble beta pleated form. Determination of SAA levels is important for assessment of renal allograft rejection, estimation of tissue damage caused by myocardial infarction and severe angina, and diagnosis of inflammation in cystic fibrosis patients and in patients infected with virus